Teams and riders
- 94 updated teams according to CQRanking and UCI (2010 shirts for 53 of them)
- C. 2800 riders
- C. 1000 free agents
- 31 dopers with a sort of injury that 'run out' when they are allowed to ride again
- C. 250 personalized skins
- Completely new photos for c. 2600 riders

Races/Stages
- 257 races in total (91 new)
- 2010 profiles for the World Championship (RR and TT) in Melbourne, Tour de France, Giro d'Italia, Tour Down Under, Tour de Suisse, Grand Prix de Québec and Grand Prix de Montréal, Grand Prix La Marseillaise and Trofeo Laigueglia.
- 42 National Championships (RR and TT total)
- 16 Youth Races
- 2010 race dates (e.g. Tour of California in May)
- Cancelled races removed
- New Time Gap system to make smaller gaps more likely
- New variants for Dauphine Libere, Tour de France, Vuelta a Espana, Paris-Nice and several National Championships

Equipment
- C. 192 frames
- C. 123 wheels
- C. 156 helmets

Graphics
- UCI Sponsor Kit (replaces the original Cyanide one)
- 2009 Tour de France podium
- Cobblestone Addon
- Miya's "Open Mouth"-addon
- New Race Category icons
- New Country Flags
- "Cyanide News" replaced with "L'Equipe"
- Improved training system

Other
- 10 new scouting zones
- Realistic Staff Names (and more staff in general)
- C. 600 Secondary Sponsors
- Cya Top Tour renamed to UCI Pro Tour
- Superprestige renamed to CQRanking*

*: The point schema is the original one. Changing it had too many negative side-effects.

Pro Tour
AG2R La Mondiale ALM AG2R
Astana AST Astana
Caisse d'Epargne GCE Caisse d'Epargne
Euskaltel - Euskadi EUS Euskaltel
Footon - Servetto FOT Footon - Servetto
Française des Jeux FDJ Française des Jeux
Garmin - Transitions GRM Garmin
Lampre - Farnese Vini LAM Lampre
Liquigas - Doimo LIQ Liquigas
Omega Pharma - Lotto OLO Omega Pharma
Quick·Step QST Quick·Step
Rabobank RAB Rabobank
Sky Professional Cycling Team SKY Sky
Team HTC - Columbia THR HTC - Columbia
Team Katusha KAT Katusha
Team Milram MRM Team Milram
Team RadioShack RSH The Shack
Team Saxo Bank SAX Saxo Bank


Pro Continental and Continental Teams
Acqua & Sapone ASA Acqua & Sapone
Adageo Energy ADG Adageo Energy
Adria Mobil ADR Adria Mobil
Amore & Vita - Conad AMO Amore & Vita
An Post - Sean Kelly SKT An Post - Sean Kelly
Andalucía Cajasur ACA Andalucía
Androni Giocattoli AND Androni Giocattoli
Atlas Personal - BMC ARH Atlas - BMC
Bahati Foundation BFN Bahati Foundation
Barbot - Siper BSP Barbot - Siper
Bbox Bouygues Télécom BTL Bouygues Télécom
Betonexpressz 2000 - Universal Caffe BUC Betonexpressz
Big Mat - Auber 93 AUB Auber 93
Bissell BPC Bissell
BMC Racing Team BMC BMC
Bretagne - Schuller BSC Bretagne - Schuller
Burgos Monumental - Castilla y Leon VMC Burgos
Caja Rural CAR Caja Rural
CarmioOro NGC CMO CarmioOro
CCC Polsat Polkowice CCC CCC Polsat
Centri della Calzatura - Cavaliere CZP Centri Calzatura
Centro Ciclismo de Loulé - Louletano CCL Loulé - Louletano
Ceramica Flaminia FLM Ceramica Flaminia
Cervélo Test Team CTT Cervélo
Cofidis, le crédit en ligne COF Cofidis
Colnago - CSF Inox CSF Colnago - CSF
Continental Team Differdange CCD Differdange
Cycling Club Bourgas CCB Club Bourgas
Cyclingteam Jo Piels CJP Jo Piels
De Rosa - Stac Plastic DER De Rosa - Stac
DHL - Author DHL DHL - Author
Fly V Australia VAU Fly V Australia
Glud & Marstrand - LRØ Rådgivning GLU Glud & Marstrand
ISD - Neri ISD ISD - Neri
Itera - Katusha TIK Itera - Katusha
Jamis - Sutter Home JSH Jamis
Jelly Belly presented by Kenda JBC Jelly Belly
Joker Bianchi TJB Joker Bianchi
Jong Vlaanderen - Bauknecht JVB Jong Vlaanderen
Kelly Benefit Strategies KBS Kelly Benefit
LA - Rota dos Móveis FRM Rota dos Móveis
Landbouwkrediet LAN Landbouwkrediet
LKT Team Brandenburg LKT Brandenburg
Madeinox - Boavista BOA Madeinox
Meridiana Kamen Team MKT Meridiana Kamen
Miche MIE Miche
Motorpoint - Marshall's Pasta MPT Motorpoint
Orbea ORB Orbea
Palmans Cras PCO Palmans Cras
Palmeiras Resort - Tavira PRT Palmeiras Resort
PSK Whirlpool - Author PSK PSK Whirlpool
Rabobank CT RB3 Rabobank CT
Rapha Condor - Sharp RCS Rapha Condor
Rock Racing RRC Rock Racing
Roubaix Lille Métropole RLM Roubaix
Saur - Sojasun SAU Saur - Sojasun
Skil - Shimano SKS Skil - Shimano
Sparebanken Vest - Ridley SPV Sparebanken Vest
Spidertech powered by Planet Energy CSM Planet Energy
Team Concordia Forsikring – Himmerland VPC Team Concordia
Team Designa Køkken - Blue Water DBW Designa Køkken
Team Kuota - Indeland TRS Kuota - Indeland
Team NetApp APP Team NetApp
Team Nutrixxion Sparkasse TSP Team Sparkasse
Team Raleigh RAL Team Raleigh
Team Sprocket Procycling SPR Team Sprocket
Team Type 1 TT1 Team Type 1
Thüringer Energie Team TET Thüringer Energie
Topsport Vlaanderen - Mercator TSV Topsport Vlaanderen
Trek Livestrong U23 TLS Trek Livestrong
UnitedHealthcare presented by Maxxis UHC UnitedHealthcare
Vacansoleil Pro Cycling Team VAC Vacansoleil
Van Vliet EBH Elshof VVE Van Vliet
Verandas Willems WIL Verandas Willems
Vorarlberg - Corratec VBG Vorarlberg - Corratec
Xacobeo - Galicia XAC Xacobeo